Liver Detox Test Description

The process of detoxification is one of the chief roles of the liver. Conditions that may be associated with an imbalance in liver function include autism, chronic fatigue, food intolerances, headaches, multiple chemical sensitivities and rheumatoid arthritis. At Perpetual Wellbeing we offer a complete liver detox test, a liver function test that gives an insight into liver health.

The Liver Detoxification Profile: The True Liver Function Test

The liver works to convert lipid-soluble xenobiotics into water-soluble substances that can be excreted from the body. It does this via a two-step process designated phase I and phase II. When the function of the liver is sub-optimal, toxins can build-up and poison the body.

What Does The Liver Detox Test Assess?

For the assessment of liver function, we use the liver detoxification profile. This test is unlike standard liver function tests which only provide a measure of hepatic damage (released hepatic enzyme levels).

In contrast, the liver detoxification test offered by Perpetual Wellbeing is a true functional test.

Specific measurements of the different phases of liver detoxification including phase I and phase II are obtained, guiding the design of effective and specific therapeutic strategies which can optimise liver function.

Key Advantages of the Liver Detox Profile

  • Assessment of phase I and phase II detoxification
  • Assessment of toxin exposure and impaired liver function
  • No hepatotoxic challenge drugs required
  • Simple first morning void urine collection

Chemical Exposure

Since World War II the quantity of synthetic chemicals that have been produced and introduced into the environment has increased exponentially. In the 1930’s only 1 million tons was produced per year, in comparison to over 200 million tons today. This increase in chemical exposure has had an impact not only on the environment but on human health.


Many of these substances including xenobiotics and heavy metals are known to affect the immune system, detoxification pathways and the central nervous system, as well as promote inflammation.

Conditions ranging from fatigue, cancer, dermatitis, renal disease, chemical sensitivities, autism and other mood disorders are associated with exposure. Ensuring optimal detoxification of these toxins is therefore a vital step for the prevention and treatment of these and other chemical associated disorders.

More about the test:

The body continually attempts to eliminate chemical toxins through enzymatic processes in the liver. Urinary D-glucaric acid is a by-product of phase I detoxification and is a valuable indicator of chemical exposure or liver damage. Urinary mercapturic acids are direct end product metabolites of conjugated xenobiotics in phase II detoxification.

The Hepatic Detoxification Profile provides a combined assessment of the urinary levels of the two analytes which gives invaluable information about exposure to xenobiotics and the capability of the liver to eliminate toxins.


Why test liver function?

The production, use and disposal of toxic chemicals and synthetic materials have increased the risk of exposure to health threatening toxins.

Causal relationships between toxic chemicals and diseases have been well established. However, many patients endure chronic symptoms that are associated with exposure to toxins before advanced stages of specific diseases are realised. Thus, there is a great demand for non-invasive laboratory tests that can timely assess chemical exposure and the capability of hepatic detoxification.


Book an online consultation or a face to face appointment at our Brisbane or Graceville clinics with one of our naturopaths and let us help you understand if an imbalance in liver function is an underlying cause of your health issues.

A test pricing guide is available here.

What We Can Help With

The team at Perpetual Wellbeing support the health and wellbeing of the whole family. We promote a more scientifically-based approach to natural healthcare, to help detect the root cause of health issues and treat patients for long-term good health.

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